Brock Purdy, Nick Bosa Ruled Out for Week 12 vs. Packers; Injury ...

The San Francisco 49ers are set to face the 7-3 Green Bay Packers on the road without their starting quarterback. QB1 Brock Purdy (right shoulder) was ruled out of the team's Week 12 contest after being a limited participant in practice on Wednesday and Thursday and sitting out of Friday's workout altogether. The 49ers third-year quarterback suffered his right shoulder injury in San Francisco's Week 11 matchup against the Seattle Seahawks.

"I don't want to say there is long term concern. We got the MRI on Monday, we really just thought he needed some rest," head coach Kyle Shanahan said on Friday. "We really weren't concerned about him not being good this week, but when he started up Thursday, it surprised him, it surprised us how (his shoulder injury) felt. So, we had to shut him down.

"I really don't know what to think of it. The MRI doesn't look like that, so it should be all right. But, the way it responded, it really is up in the air for next week. We'll have to see on Monday."

Since his first start for the 49ers in Week 14 of the 2022 season, Purdy has missed just one game, the 2023 regular season finale versus the Los Angeles Rams. With Purdy out of the lineup versus the Packers, ninth-year pro Brandon Allen will be leading the 49ers offense on Sunday at Lambeau Field.

Allen was named the 49ers backup quarterback in September. He's made a total of nine starts in his NFL career with his most recent start coming in the final game of the 2021 season as a member of the Cincinnati Bengals. In that contest, Allen connected on 15-of-29 pass attempts for 136 yards and a touchdown in the team's narrow loss to the Cleveland Browns.

Defensive lineman Nick Bosa, who missed all three practices this week due to a hip/oblique injury, was also ruled out for Sunday. Meanwhile, left tackle Trent Williams enters the weekend as questionable.